This is a white paper from the Office of Women's Health that was developed by conducting a review of the literature focused on topics around opioid use disorders and women, as well as consulting with subject matter experts. This report begins by providing an overview of the opioid epidemic and what it means for women. Issues of prevention and treatment are then explored, all with the lens of the unique or pronounced needs of women. The paper concludes with a resource section with links to key information.